Objectives
The overall objective of the
nanoDNAsequencing Project is to develop a cheap and high-speed
DNA sequencing technology. This will be achieved trough the
following steps:
-
Fabrication of single wall
carbon nanotube junction-gate for molecular recognition
-
Exploring the interaction
and conduction mechanisms between DNA and nanotube-electrode
and DNA-nanopore
-
Electrical
characterization of the DNA nucleobases
-
Development of model nano-electronic
device for single-base DNA electrical characterization and
decoding
The project is organized in 7
workpackages, distributed over 36 months. Each workpackage
focuses on a specific aspect of the proposal and has its own
leader, who will coordinate the partners efforts on the
different topics. The overall project will be directed by the
coordinator with the support of a task and work packages
leaders.
The groups from EPFL and
University of Regensburg will use their demonstrated skills and
expertise in order to fabricate a single wall carbon nanotube
junction with gap between electrodes of few nanometers. This
device will be fabricated using transmission electron beam
ablation lithography and by oxygen plasma etching. This
objective will be achieved through the permanent and
collaborative exchange of knowledge with the other consortium
members. The theoretical part of consortium (Trinity College
Dublin and Institute of Physics Belgrade) will perform the
investigations of the interaction and conduction mechanisms
between DNA and nanotube-electrode through the calculation of
electronic structure, conductance and current-voltage
characteristics using DFT-Keldysh-NEGF approach and DNA
translocation. The electrical characterization of DNA will be
performed by the synergy of all partners. Biochemical issues
will be addressed by the UR group. They will synthesize and
prepare DNA materials with well-defined characteristics.
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