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Objectives

The overall objective of the nanoDNAsequencing Project is to develop a cheap and high-speed DNA sequencing technology. This will be achieved trough the following steps:

  1. Fabrication of single wall carbon nanotube junction-gate for molecular recognition
     

  2. Exploring the interaction and conduction mechanisms between DNA and nanotube-electrode and DNA-nanopore
     

  3. Electrical characterization of the DNA nucleobases
     

  4. Development of model nano-electronic device for single-base DNA electrical characterization and decoding

The project is organized in 7 workpackages, distributed over 36 months. Each workpackage focuses on a specific aspect of the proposal and has its own leader, who will coordinate the partners efforts on the different topics. The overall project will be directed by the coordinator with the support of a task and work packages leaders.

The groups from EPFL and University of Regensburg will use their demonstrated skills and expertise in order to fabricate a single wall carbon nanotube junction with gap between electrodes of few nanometers. This device will be fabricated using transmission electron beam ablation lithography and by oxygen plasma etching. This objective will be achieved through the permanent and collaborative exchange of knowledge with the other consortium members. The theoretical part of consortium (Trinity College Dublin and Institute of Physics Belgrade) will perform the investigations of the interaction and conduction mechanisms between DNA and nanotube-electrode through the calculation of electronic structure, conductance and current-voltage characteristics using DFT-Keldysh-NEGF approach and DNA translocation. The electrical characterization of DNA will be performed by the synergy of all partners. Biochemical issues will be addressed by the UR group. They will synthesize and prepare DNA materials with well-defined characteristics.
 

 

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© 2009 - nanoDNAsequencing project: “NanoTools for Ultra Fast DNA Sequencing”