The nanoDNAsequencing project aims to investigate a novel single-molecule DNA sequencing nanotechnology protocol (gene sequencer) that has potential to sequence a molecule of genomic dimensions in hours without expensive and fault sensitive DNA copying steps and chemical reactions.

The gene sequencer is based on the electrical characterization of individual nucleobases, while DNA passes through a nanopore with integrated nanotube side-electrodes.

The research proposed here will provide a unique combination of state of the art capabilities for cutting and usage of single wall carbon nanotubes as electrodes forming a lithographically fabricated “nanogap” with single-nanometer precision.

In addition, the synergy of consortium resources for electrical characterization and leading theoretical skills for nanotransport will provide new solutions and information for an answer on the proof-of-principle question: is it possible to detect different types of DNA bases by their electrical properties?


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© 2009 - nanoDNAsequencing project: “NanoTools for Ultra Fast DNA Sequencing”